Influence of patient age on angioarchitecture of brain arteriovenous malformations.

نویسندگان

  • S W Hetts
  • D L Cooke
  • J Nelson
  • N Gupta
  • H Fullerton
  • M R Amans
  • J A Narvid
  • P Moftakhar
  • H McSwain
  • C F Dowd
  • R T Higashida
  • V V Halbach
  • M T Lawton
  • H Kim
چکیده

BACKGROUND AND PURPOSE The imaging characteristics and modes of presentation of brain AVMs may vary with patient age. Our aim was to determine whether clinical and angioarchitectural features of brain AVMs differ between children and adults. MATERIALS AND METHODS A prospectively collected institutional data base of all patients diagnosed with brain AVMs since 2001 was queried. Demographic, clinical, and angioarchitecture information was summarized and analyzed with univariable and multivariable models. RESULTS Results often differed when age was treated as a continuous variable as opposed to dividing subjects into children (18 years or younger; n = 203) versus adults (older than 18 years; n = 630). Children were more likely to present with AVM hemorrhage than adults (59% versus 41%, P < .001). Although AVMs with a larger nidus presented at younger ages (mean of 26.8 years for >6 cm compared with 37.1 years for <3 cm), this feature was not significantly different between children and adults (P = .069). Exclusively deep venous drainage was more common in younger subjects when age was treated continuously (P = .04) or dichotomized (P < .001). Venous ectasia was more common with increasing age (mean, 39.4 years with ectasia compared with 31.1 years without ectasia) and when adults were compared with children (52% versus 35%, P < .001). Patients with feeding artery aneurysms presented at a later average age (44.1 years) than those without such aneurysms (31.6 years); this observation persisted when comparing children with adults (13% versus 29%, P < .001). CONCLUSIONS Although children with brain AVMs were more likely to come to clinical attention due to hemorrhage than adults, venous ectasia and feeding artery aneurysms were under-represented in children, suggesting that these particular high-risk features take time to develop.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cerebral arteriovenous malformations: the value of radiologic parameters in predicting response to radiosurgery.

PURPOSE To define the morphological patterns of cerebral arteriovenous malformations (AVMs) that influence their response to radiosurgery at 2 years. METHODS We retrospectively reviewed the yearly MR and angiographic follow-up studies in 102 patients who had radiosurgical treatment for cerebral AVMs between 1990 and 1992. Parameters studied were maximum length and volume of the nidus, positio...

متن کامل

Micro-arteriovenous malformations of the brain: superselective angiography in diagnosis and treatment.

PURPOSE We assessed the usefulness of superselective angiography in patients with micro-arteriovenous malformations. PATIENTS AND METHODS Five patients had superselective angiography for either diagnosis or treatment of brain arteriovenous malformations having a nidus of less than 1 cm. All patients presented with an intracerebral hematoma. RESULTS In one patient superselective angiography ...

متن کامل

Angioarchitecture of brain arteriovenous malformations and the risk of bleeding: an analysis of patients in northeastern malaysia.

BACKGROUND Central nervous system arteriovenous malformation (AVM) is a vascular malformation of the brain and involves entanglement of veins and arteries without an intervening capillary bed. Affecting predominantly young male patients, AVM presents with different clinical manifestations namely headache, seizures, neurological deficit and intracranial haemorrhage. The patients who present acut...

متن کامل

Large and deep brain arteriovenous malformations are associated with risk of future hemorrhage.

BACKGROUND AND PURPOSE The correlation between features present in brain arteriovenous malformations (AVMs) such as size, location, and angioarchitecture at presentation with subsequent risk of hemorrhage may be valuable in predicting the behavior of AVMs and therefore guiding management. METHODS We prospectively followed up 390 patients with brain AVMs at the University of Toronto Vascular M...

متن کامل

Multimodal angiographic assessment of cerebral arteriovenous malformations: a pilot study

PURPOSE We describe our protocol of three-dimensional (3D) Roadmap intracranial navigation and image fusion for analysis of the angioarchitecture and endovascular treatment of brain arteriovenous malformations (AVMs). METHODS We performed superselective catheterization of brain AVMs feeders under 3D-Roadmap navigation. Angiograms of each catheterized artery on two registered orthogonal views ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 35 7  شماره 

صفحات  -

تاریخ انتشار 2014